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Animal-Origin-Free Isn’t Optional—It’s Critical to CGT Success

InVitria’s recombinant, animal-origin-free, chemically defined supplements support sterility, consistency, and regulatory compliance in cell and gene therapy biomanufacturing.

Trusted by Leading Companies

Improve Yield and Safety—Without Animal-Derived Raw Materials

Switch to recombinant, animal-origin-free components built for CGT.

Animal- and blood-derived components introduce unnecessary risk to your cell and gene therapy workflows—risk that regulators, investors, and patients can’t afford. InVitria’s recombinant, chemically defined supplements give you complete control over your media while maintaining performance across every stage of development.

✅ Eliminate contamination risk and supply variability
✅ Improve batch-to-batch consistency and scalability
✅ Meet global regulatory expectations with cGMP-grade solutions
✅ Enhance cell viability, productivity, and downstream yields
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Chemically Defined Products for Cell & Gene Therapy

Optibumin® 25

Recombinant Human Serum Albumin

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A 25% recombinant human serum albumin in 100 mL bags, designed for closed-system biomanufacturing. Enhances stability, consistency, & yield in Cell & Gene Therapy workflows from research to cGMP.

Optiferrin®

Recombinant Human Transferrin

OPTIFERRIN-Family

A recombinant human transferrin that improves vector yield, transfection efficiency, and cell growth in HEK293 and other key CGT production cell lines. Scalable for research through clinical manufacturing.

OptiLeukin™ 2

Recombinant Human Interleukin-2

OptiLeukin 2 Product Image

A high-purity, animal-/ bacteria-free recombinant human IL-2 in lyophilized powder form. Supports consistent T & NK cell expansion in serum-free, chemically defined workflows from research to manufacturing.

ITSE+A AF™

Cell Culture Media Supplements

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Defined supplement with insulin, transferrin, selenium, ethanolamine, and rAlbumin to enhance viability, stability, and performance in worry-free, animal-origin-free Cell & Gene Therapy manufacturing.

Explore the Full InVitria Portfolio

From albumin to transferrin and complete media kits—discover recombinant, animal-origin-free solutions optimized for every step of your CGT workflow.

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What We’re Talking About

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APP NOTE: Preserving Lentiviral Titer During Sterile Filtration Using Recombinant Albumin

Sterile filtration can significantly reduce lentiviral recovery during downstream processing. This application note highlights how recombinant human albumin helped preserve lentiviral titer and improve recovery compared to filtration without albumin supplementation. The data supports the use of animal-origin-free recombinant albumin to improve consistency and performance in viral vector manufacturing. Presented at ASGCT 2026.

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APP NOTE:  Recombinant Albumin Improves Cytokine Recovery and Functional Stability 

Cytokines and growth factors are costly, fragile proteins that can lose activity at dilute concentrations due to aggregation, surface adsorption, and oxidation. This application note shows how Optibumin® 25 helps improve cytokine recovery and preserve functional bioactivity during storage, including room-temperature conditions. The data supports recombinant albumin as an animal-origin-free carrier protein for more consistent cytokine and growth factor formulations. 

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POSTER: Better Cells, Better Outcomes: Improving CAR-T with Animal-Free Cryopreservation and Wash Solutions

Even small changes in downstream steps—like washing and cryopreservation—can impact CAR-T quality, viability, and consistency. This poster shows how InVitria’s Optibumin® 25 improves viable T cell recovery, memory phenotype preservation, and post-thaw proliferation compared to PBS and plasma-derived HSA. As Presented at ISCT 2025,& BPI Europe 2025 & ASGCT 2025

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INFOGRAPHIC: How Defined Components Improve CAR-T Manufacturing Outcomes

From inconsistent yields to regulatory delays, traditional cell culture inputs introduce risk at every stage. This infographic breaks down how InVitria’s animal-origin-free, recombinant components streamline CAR-T workflows—enhancing cell viability, reproducibility, and regulatory readiness.

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APP NOTE: Sustained T Cell Proliferation and Early Memory Retention with OptiLeukin™ 2 Recombinant IL-2

IL-2 is essential for T cell expansion—but not all IL-2 is created equal. This quick read shares real-world data showing how OptiLeukin™ 2, a high-purity, animal-origin-free recombinant IL-2, delivers robust proliferation and preserves early memory phenotypes. Designed for consistency, safety, and scale, it’s a seamless replacement for E. coli–derived IL-2 in GMP workflows.

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Why Do Some Biologics Cross the Finish Line—While Others Crash and Burn?

Even promising cell and gene therapies can fail—often due to overlooked CMC challenges. This quick read explores real-world case studies and offers practical steps to avoid costly late-stage setbacks, including the role of animal-origin-free materials and early CMC planning.

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How Regulatory Bodies Are Driving the Shift to Animal-Origin-Free Solutions in Cell Therapy and Vaccine Development

Global regulators are moving away from animal-derived components in CGT manufacturing. Learn why animal-origin-free materials are becoming the new standard—and how they support safer, more consistent therapies.

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Scaling Innovation: How DiscGenics and InVitria are Leading the Future of Cell Therapy

See how DiscGenics scaled from manual methods to cGMP-ready manufacturing with InVitria’s animal-free solutions—proving what’s possible when innovation meets process control.​

Why we stand out

AoF & Chemically Defined Solutions

InVitria offers high-quality, animal-free recombinant proteins and supplements that ensure consistency and safety in cell culture and biologics manufacturing. Our chemically defined solutions eliminate the variability and ethical concerns associated with traditional animal-derived supplements.

Enhanced Performance and Reliability

Our products are designed to improve the performance and reliability of your research and manufacturing processes. By providing a consistent and controlled environment, InVitria's offerings help you achieve superior results and reproducibility in your scientific endeavors.

Simplified Regulatory Approval Process

InVitria's animal-origin-free products simplify the regulatory approval process by eliminating concerns related to animal-derived contaminants. This streamlines your path to market, saving you time and resources while ensuring compliance with stringent regulatory standards.

About InVitria

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Our Company

InVitria is dedicated to revolutionizing the world of cell culture and biologics manufacturing with our high-quality, animal-free recombinant proteins and supplements. We offer scientists and biomanufacturers innovative solutions that address the limitations of traditional supplements such as serum. Our products are reliable, chemically defined, and free from animal origins, ensuring improved consistency and performance. By simplifying the regulatory approval process, InVitria enhances safety and reliability for our clients. Our commitment to quality and innovation helps drive advancements in scientific research and biomanufacturing.