In contrast to many therapeutic medicines, vaccines are specifically administered to healthy people to help prevent illness. Therefore, the need for reliable, safe and high-performing cell culture systems and media, free of contamination from adventitious pathogens like viruses and prions, is critical. Furthermore, cell-based biomanufacturing of vaccines is media-intensive and may require quantities of serum that would be impractical and cost-prohibitive to source. This application note explores the use of OptiVERO Serum Free Media (SFM) (product No.777OCM090) when expanding Vero cell lines to support virus production.
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